Pridiyathorn Science Journal https://li04.tci-thaijo.org/index.php/psj <p>เผยแพร่ผลงานวิชาการสู่หน่วยงานภายนอกและความก้าวหน้าทางวิชาการในสาขาต่างๆของคณะ และยังเป็นการสร้างเครือข่ายเผยแพร่ข้อมูลทางวิชาการ ทางด้านวิทยาศาสตร์และเทคโนโลยี สาขาต่างๆ ประกอบด้วย สาขาชีววิทยา สาขาฟิสิกส์ สาขาเคมี และสาขาคณิตศาสตร์ สถิติและสารสนเทศ และอื่นๆ วารสารตีพิมพ์เผยแพร่ 2 ฉบับต่อปี ดังนี้ ฉบับที่ 1 (มกราคม-มิถุนายน) และฉบับที่ 2 (กรกฎาคม-ธันวาคม)</p> <p><strong>วัตถุประสงค์</strong></p> <ol> <li>ส่งเสริมให้บุคลากรทั้งภายในและภายนอกหน่วยงานได้เผยแพร่ผลงานวิชาการสู่หน่วยงานภายนอกและความก้าวหน้าทางวิชาการในสาขาต่างๆของคณะ</li> <li>สร้างเครือข่ายเผยแพร่ข้อมูลทางวิชาการ ตลอดจนถ่ายทอดเทคโนโลยีผลงานทางวิชาการในรูปแบบออนไลน์</li> </ol> <p><strong>ขอบเขต</strong></p> <p>บทความวิจัย (Research article) และบทความวิชาการ (Academic article) ทางด้านวิทยาศาสตร์และเทคโนโลยี สาขาต่าง ๆ ประกอบด้วย สาขาชีววิทยา สาขาฟิสิกส์ สาขาเคมี สาขาคณิตศาสตร์ สถิติ และสารสนเทศ สาขาศาสตร์การสอนด้านคณิตศาสตร์และวิทยาศาสตร์</p> คณะวิทยาศาสตร์และเทคโนโลยี มหาวิทยาลัยนราธิวาสราชนครินทร์ en-US Pridiyathorn Science Journal <p>ข้อความลิขสิทธิ์ เติมด้วยค่ะ</p> Extraction and Determination of Curcuminoids in Turmeric Capsules https://li04.tci-thaijo.org/index.php/psj/article/view/1151 <p>The purpose of this research was to study the curcuminoid content from crude extracts and determination of curcuminoids from turmeric capsules.Chemical composition of turmeric contains curcuminoids, it is a yellow substance extracted from turmeric rhizomes. Determination of curcuminoids by spectroscopic techniques. Crude extract from methanol, curcuminoid content was the highest at 62.51%, followed by acetone crude extract at 43.56% and dichloromethane at 39.24%, respectively whereas the study of curcuminoids from 3 brands of turmeric capsules found that Langkasuka brand, the amount of curcuminoids was the highest at 11.50%, followed by Abhaibhubejhr brand, 10.39%, and Ouay-An-Osoth brand, 9.71 %, respectively.</p> Charuwan Daengrot Fuzana Maseng Waeyae Samoh Sirinut Duangsook Seeyah Kareng Arwiya Doloh Patima Phainuphong Copyright (c) 2023 https://creativecommons.org/licenses/by-nc-nd/4.0 2023-10-04 2023-10-04 2 1 1 8 Solvent Optimization of Pitang Leaves (Gynochthodes sublanceolata Miq.) Extraction for Bacterial Growth Inhibition https://li04.tci-thaijo.org/index.php/psj/article/view/1152 <p>Nang dam or Pitang<em>&nbsp;(Gynochthodes sublanceolata</em>&nbsp;Miq.) is a medicinal plant, found in southern Thailand. The leaves are mostly used as a natural food coloring agent and the studies on the pharmacological properties of this plant are needed. The aim of this study was to compare the effectiveness of solvents used for extracting Nang dam leaves and investigate their antibacterial activity. Water, ethanol, acetone, and ethyl acetate were used to extract the leaves. The extraction yield of the crude ranged from 1.14 to 3.2. The highest yield was found in the water-soluble extract (3.2%). However, acetone-soluble extract rendered the highest antibacterial activity using the disc diffusion method, this concluded that acetone was the suitable solvent for extracting Nang dam leaves. The average inhibition zone for&nbsp;<em>Bacillus subtilis</em>&nbsp;ATCC 6051 was 10.00±0.667 mm,&nbsp;<em>and Staphylococcus aureus</em>&nbsp;ATCC 6538P was 6.90±0.875 mm, respectively. Therefore, the acetone extract of Nang dam leaves inhibited Gram-positive bacteria more effective than other solvents. However, its pharmacological properties, such as antioxidant activity and toxicity in living organisms required further studies.</p> Charuwan Pradabsang Suchada Saengwiman Supat Srisawat Inun Yipong Copyright (c) 2023 https://creativecommons.org/licenses/by-nc-nd/4.0 2023-10-04 2023-10-04 2 1 9 23 Predicting Diabetes using Deep Belief Network https://li04.tci-thaijo.org/index.php/psj/article/view/1153 <p>Diabetes is a common disease affecting millions of people in the United States. The prevalence of diabetes has been steadily increasing over the past few decades. Left untreated diabetes leads to a risk factor for multiple complications such as heart disease, stroke, kidney and nerve damage. However, diabetes can be effectively managed when early diagnosed. Recent clinical data have applied various advanced technologies to diagnose or predict people with diabetes. Therefore, this paper aims to&nbsp; predict diabetes by using a Deep Belief Network (DBN) with Rectified Linear Unit (ReLU) activation function. Learning parameters from data through unsupervised path using minimized contrastive divergent algorithm, followed by supervised path using back-propagation algorithm. Diabetes Dataset from the National Institute of Diabetes and Digestive and Kidney Diseases was used, consisting of &nbsp;female patients aged at least 21 years old of Pima Indian heritage. The result shows that the DBN with ReLU activation function provides an 81% accuracy in diabetes prediction.</p> Sureeluk Ma Marusdee Yusoh Nitinun Pongsiri Copyright (c) 2023 https://creativecommons.org/licenses/by-nc-nd/4.0 2023-10-04 2023-10-04 2 1 24 32 Ferrocene and Its Derivatives for Medical Applications https://li04.tci-thaijo.org/index.php/psj/article/view/1154 <p>Ferrocene, also known as dicyclopentadienyliron, is classified as one of the organometal compounds that contain a transition metal (iron) and 2 cyclopentadienyl rings in its sandwich-liked molecule. Due to its structural characteristic, this can also be called&nbsp;“Sandwich compound” or “Metallocene”. Ferrocene and its derivatives have been studied extensively, especially in the field of medicine, for example, their kinase inhibiting properties, which inactivate malfunctioned enzymes resulting in the reduction of the occurrence of certain diseases such as cancers, neurological diseases, diabetes, heart disease, and etc. This review paper is intended to elaborate on the sequence of ferrocene compounds and their derivatives in medical application. The data from various research groups have highlighted some important properties of metallocene compounds as pharmaceutical agents. Therefore, the synthesis of ferrocene compounds has become more widespread and well-known since the discovery of ferrocene.</p> Supojjanee Sansook Kanokwan Phumivanichakit Aslan Hilae Copyright (c) 2023 https://creativecommons.org/licenses/by-nc-nd/4.0 2023-10-04 2023-10-04 2 1 33 43 Factors and reduction strategies of Polycyclic Aromatic Hydrocarbons (PAHs) Formation in Charcoal-Grilled Food Products https://li04.tci-thaijo.org/index.php/psj/article/view/1155 <p>Nowadays, grilled food is very popular, especially charcoal-grilled food since it produces color, unique smell, and taste. Charcoal grilling can lead to the contamination of PAHs in food which are carcinogens. Therefore, it is important to understand the mechanisms of PAHs formation to find solutions for reducing PAHs in charcoal-grilled foods. Although the mechanism of its occurrence is still unclear, previous research has assumed the mechanism of PAHs formation in charcoal-grilled food as following reactions: incomplete combustion, pyrolysis, the Maillard reaction, lipid oxidation and degradation. The reaction depends on grilling process factors including the amount of fat in the meat, the component of marinate meat before grilling, temperature, cooking time, and charcoal used for grilling. The methods for controlling the factors that cause PAHs formation are as follows: equipment design for reducing the smoke during grilling process and oil dripping onto the charcoal, using high-quality charcoal, burning whole charcoal before grilling food, partially cooked meat before grilling, prevention of oil drop on the charcoal by wrapping the meat before grilling, which can reduce PAHs formation in charcoal-grilled food. For future study guidelines, it is interesting to study the cofactors of PAHs in charcoal-grilled food to determine the relationships between the factors contributing to PAHs in charcoal-grilled food.</p> Madeena Noitubtim Piyaporn Wangsirikul Aslan Hilae Copyright (c) 2023 https://creativecommons.org/licenses/by-nc-nd/4.0 2023-10-04 2023-10-04 2 1 44 58