Plant lectins have antagonistic effects against Coronavirus family: Natural products can control Coronaviral infections: A review
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Abstract
From the end of December 2019, Corona Virus Disease – 19 (COVID – 19) is the fear of people throughout the world. The causal organism behind COVID – 19 is SARS – CoV – 2 (Severe acute respiratory syndrome corona virus). This virus creates respiratory problems in human beings. WHO declared COVID – 19 as a pandemic disease because of its severe infection development capability. Like many other enveloped viruses, SARS – CoV – 2 carries glycoproteins on their surface. These glycoproteins are mainly responsible for the infection processes. They have involved in the receptor binding phenomenon. These glycoproteins are also involved in retrovirus particle and host cell membrane fusion. So, they may be potential targets for the development of novel corona viral therapies. Carbohydrate - Binding Agents (commonly called CBA) have antiviral activity towards the Corona virus. Plant lectins have anti-viral activities against Coronavirus species. In this review, we discussed thoroughly about the role of plant lectins in destroying Coronavirus infection. Plant lectins may be the potential source of herbal drugs of COVID – 19.
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