Phytochemical profiling and antimicrobial evaluation of zinc oxide nanoparticles from the leaves of Anisomeles malabarica (L) R. Br (lamiaceae)
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Abstract
The results of qualitative phytochemical analysis reflected the occurance of alkaloids, flavonoids, terpenoids, phenols and tannins, whereas the quantitative HPLC analysis showed the occurence of compounds such as luteolin, β-Thujone, carveol, p.coumaric acid, quercetin, β-pinene and myrtenol. UV-visible spectrophotometer analysis of green synthesized ZnO NPs showed the absorption peak maximum at 368 nm, FTIR analysis result showed the N=O stretch nitrogen groups, C=O stretch anhydrides, =C-N stretch alkenes. SEM images reflected a cluster of spherical evenly distributed ZnO NPs with the size of 50.4 nm in size and EDX pattern exhibited strong emission energy at 1.743keV. The antibacterial activity of ZnO NPs were tested against E. coli, Enterobacter, Bacillus resulted the maximum zone of growth inhibition on all the bacterial strains. The outcome of the present study revealed that A. malabarica, mediated ZnO nanoparticles is found to be more effective than crude extracts. Further research is needed to explore the molecular action, which will be benefited to the scientific communities as well as pharmaceutical industries for developing plant-based drugs in future.
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