Antimicrobial activity from endophytic fungi isolated from plant leaves in Dipterocarpous forest at Viengsa district Nan province, Thailand
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Abstract
Eleven fungal endophytes representing different morphotaxa were characterized from 68 cultures, which were isolated from 4 species of Dipterocapous trees (Dipterocarpus tuberculatus Roxb., Shorea obtusa Wall., Shorea siamensis Miq. and Dalbergia oliveri Gamble.) growing in the Dipterocapous forest at Viengsa district, Nan province. Species of Phyllosticta spp. (15 isolates), Nodulisporium spp. (13 isolates) and Xylaria sp.1 (10 isolates) were the most frequently found. All endophytic fungal isolates were tested for potential production of bioactive metabolites. They were tested for antimicrobial activity against pathogenic microorganisms such as Staphylococcus aureus, Bacillus subtilis, Pseudomonas aerogenosa, Escherichia coli and Candida albicans by the paper disk susceptibility test. They inhibited the growth of Gram positive bacteria more than Gram negative bacteria. Candida albicans was inhibited only by Nodulissporium sp. (DT6) and Xylaria sp.1 (DO9).
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