Ferrocene and Its Derivatives for Medical Applications


  • Supojjanee Sansook
  • Kanokwan Phumivanichakit
  • Aslan Hilae


Ferrocene, Organometallic, Sandwich-compound, Metallocene, Kinase-inhibitor


Ferrocene, also known as dicyclopentadienyliron, is classified as one of the organometal compounds that contain a transition metal (iron) and 2 cyclopentadienyl rings in its sandwich-liked molecule. Due to its structural characteristic, this can also be called “Sandwich compound” or “Metallocene”. Ferrocene and its derivatives have been studied extensively, especially in the field of medicine, for example, their kinase inhibiting properties, which inactivate malfunctioned enzymes resulting in the reduction of the occurrence of certain diseases such as cancers, neurological diseases, diabetes, heart disease, and etc. This review paper is intended to elaborate on the sequence of ferrocene compounds and their derivatives in medical application. The data from various research groups have highlighted some important properties of metallocene compounds as pharmaceutical agents. Therefore, the synthesis of ferrocene compounds has become more widespread and well-known since the discovery of ferrocene.


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How to Cite

Sansook, S., Phumivanichakit, K., & Hilae, A. (2023). Ferrocene and Its Derivatives for Medical Applications. Pridiyathorn Science Journal, 2(1), 33–43. Retrieved from https://li04.tci-thaijo.org/index.php/psj/article/view/1154



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